Anti-Acne Cosmetic Raw Material Adapalene106685-40-9

Basic Info

Model NO.	106685-40-9
Colour	White
1	106685-40-9
2	C28h28o3
3	106685-40-9
Transport Package	Alum Foil Bag/Carton/Drum
Specification	1kg/alu bag, 25kg/drum
Trademark	AHRC
Origin	China
HS Code	291450909
Production Capacity	50000kg/Month

Product Description

Common Name	Adapalene
CAS Number	106685-40-9	Molecular Weight	412.520
Density	1.2±0.1 g/cm3	Boiling Point	606.3±55.0 °C at 760 mmHg
Molecular Formula	C28H28O3	Melting Point	319-322ºC

Function..........................................................................................................................

Adapalene is a retinoic acid compound that has been shown to have anti-inflammatory properties in in vivo and in vitro models of inflammation, is chemically stable, and is not easily decomposed by air and light. The mechanism of action is the same as that of retinoic acid, which can bind to specific retinoic acid nuclear receptors, the difference is that adapalene does not bind to cytoplasmic receptors that bind to proteins. Adapalene has been shown to treat acne in an animal model established in mice in a dermal drug test, and also has an effect on acne vulgaris and differentiation processes. The mechanism of action is to reduce the formation of microcomedones by normalizing the differentiation of hair cells on the hair follicles. in standard anti-inflammatory assays in vivo and in vitro. Adapalene is more effective than retinoic acid, it can inhibit the chemotactic reaction of human polynuclear leukocytes, and can inhibit the metabolism of polymorphonuclear phylum by inhibiting the transformation of arachidonic acid into inflammatory mediators through lipid oxidation. , thereby alleviating inflammatory responses mediated by cellular responses. For the treatment of vulgar cutaneous acne characterized by pimples, papules and pustules. It can also be used to treat acne on the face, chest and back.
Cleaning is the first step in skin care

Sun exposure, dust, skin metabolites and cosmetics will form dirt on the skin surface, so cleaning is the first step in skin care. Sensitive skin should use safe cosmeceutical products to cleanse.

Hydration and sun protection are key

Skin care products have a certain order of use. If the order is wrong, the effect will be weakened. Generally speaking, the products with the smallest molecular weight are used first, and the products with the largest molecular weight are used in order. The usual order is: lotion, essence, lotion, and cream. Sun protection is the last step in skin care. The main damages caused by excessive UV exposure to the skin include sunburn, suntanning, and photoaging.

Proper whitening and anti-wrinkle

Whitening and anti-wrinkle are enhanced skin care on top of basic skin care, aimed at people with whitening and anti-wrinkle needs. Whitening products are usually acidic, which can cause dry skin after use, so use with moisturizing products.